<div id="app">{{ message }}</div>

<script type="module">
  import { createApp, ref } from 'https://unpkg.com/vue@3/dist/vue.esm-browser.js'

  createApp({
    setup() {
      const message = ref('Hello Vue!')
      return {
        message
      }
    }
  }).mount('#app')
</script>

解决方案将代码放在html文件中成功