堆栈如下：

 Caused by: java.lang.IllegalAccessException: java.lang.Class<com.MainActivity> is not accessible from java.lang.Class<android.app.AppComponentFactory>
        at java.lang.Class.newInstance(Native Method)
        at android.app.AppComponentFactory.instantiateActivity(AppComponentFactory.java:69)
        at android.support.v4.app.CoreComponentFactory.instantiateActivity(CoreComponentFactory.java:43)
        at android.app.Instrumentation.newActivity(Instrumentation.java:1215)
        at android.app.ActivityThread.performLaunchActivity(ActivityThread.java:2862)
        at android.app.ActivityThread.handleLaunchActivity(ActivityThread.java:3079) 
        at android.app.servertransaction.LaunchActivityItem.execute(LaunchActivityItem.java:78) 
        at android.app.servertransaction.TransactionExecutor.executeCallbacks(TransactionExecutor.java:108) 
        at android.app.servertransaction.TransactionExecutor.execute(TransactionExecutor.java:68) 
        at android.app.ActivityThread$H.handleMessage(ActivityThread.java:1836) 
        at android.os.Handler.dispatchMessage(Handler.java:106) 
        at android.os.Looper.loop(Looper.java:193) 
        at android.app.ActivityThread.main(ActivityThread.java:6702)

原因：

你的activity 不是public 的 ！

有问题的声明方式：

class MainActivity extends BaseActivity {
    @Override
    protected void onCreate(@Nullable Bundle savedInstanceState) {
        super.onCreate(savedInstanceState);
        setContentView(R.layout.main_layout);
    }
}

需要改成下面这样：

public class MainActivity extends BaseActivity {
    @Override
    protected void onCreate(@Nullable Bundle savedInstanceState) {
        super.onCreate(savedInstanceState);
        setContentView(R.layout.main_layout);
    }
}